Chronic active viral persistence versus host immune mediated pathology: an analysis and manipulation of the balance.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1006592

Funding Status
Closed

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Funded Activity Summary

Our robust ability to mount an immune response and clear infections is tempered by the possibility of promoting autoimmunity. Several host genes regulate immunity. Viruses like HIV have exploited these to abrogate antiviral immunity. This project attempts to define host factors that promote chronic infection. This will be extremely valuable in understanding the vulnerabilities of our immune system and provide an insight into how we can treat chronic infections.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $418,658.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cells | chronic infection | cytokines | hepatitis B infection | hepatitis C virus | human immunodeficiency virus (HIV) | virus pathogenesis

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