Protein recognition of small RNAs in innate immunity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1006590

Funding Status
Closed

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Funded Activity Summary

Protein-RNA interactions are critical in the immune response to virus infections. Small interfering RNAs (siRNAs) are important tools in the discovery of gene function and have great potential for therapy against viral infections and cancer, but can also activate the innate immune system. By characterising the determinants of small RNA sensing by the sensors of the immune system and the protein-RNA interactions involved, we will gain new insights into the design of siRNAs for use in the clinic.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $666,417.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer therapy | immune response | inflammation | inflammatory diseases | viral disease | viral infection

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