Neurogenic diarrhoea: lessons from cholera toxin and related bacterial exotoxins

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1006453

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Many bacteria that cause diarrhoea act via the gut’s own nervous system to massively increase the transport of water and salt into the lumen of the intestine. In this project we will investigate mechanisms that lead to this over-excitation of the gut’s nervous system to test the idea that this is due to a change in the properties of the final nerve cells in the normal pathway that controls water transport. This will identify novel sites for drug treatments of diarrhoea.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $543,818.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autonomic Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cholera | diarrhoea | enteric nervous system | intestinal mucosa | ion transport | irritable bowel syndrome (IBS) | traveller's diarrhoea

Related Links