Protein Disulphide Isomerase and Motor Neuron Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1006141

Funding Status
Closed

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Funded Activity Summary

Motor Neuron Disease (MND) patients currently face a bleak future. In the common global form of disease, the average length of survival after diagnosis is 31 months. Current therapies have at best a modest effect on the course of the disease with little or no benefit in terms of overall patient survival. We have new evidence that a protein called PDI can prevent the motor neuron cells from dying in MND and hence this may be a novel therapeutic target for both sporadic and familial forms of MND.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $307,524.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

amyotrophic lateral sclerosis | motor neuron disease (MND) | neurodegeneration | neurodegenerative disorders | neuromuscular diseases | neuroscience

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