Defining the role of the PSA-related kallikrein serine proteases in hormone dependent cancer progression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1005717

Funding Status
Closed

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Funded Activity Summary

Kallikreins are a family of 15 proteins, related to the prostate cancer biomarker PSA, that have potential as biomarkers for hormone dependent cancers such as prostate and ovarian cancer. Prof Judith Clements and her team discovered that kallikreins induce resistance to chemotherapy in ovarian cancer and are found in prostate cancer bone disease. Her research will determine the underlying mechanisms of kallikrein action and their potential as new biomarkers or treatment targets for these diseases.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2016

Funding Scheme: Research Fellowships

Funding Amount: $880,454.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer genetics | genomics | kallikreins | ovarian cancer | prostate cancer | proteomics | translational research

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