Mitochondrial ribosomal pentatricopeptide domain proteins regulate protein synthesis in health and disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1005030

Funding Status
Closed

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Funded Activity Summary

Mitochondria in our cells regulate energy production from food and play an important role in health and disease. Defects in mitochondrial protein synthesis lead to severe neurodegenerative and sensory diseases and may contribute to cancer and ageing. This research aims to investigate the role of mitochondrial proteins that regulate translation in mitochondrial diseases. Characterisation of these proteins provides an unexplored resource of potential disease modulators and drug targets.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $444,108.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA binding proteins | energy metabolism | mitochondrial DNA (mtDNA) | mitochondrial disease | mitochondrial function | respiratory chain

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