Targetting the CIB1-sphingosine kinase interaction in oncogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1004695

Funding Status
Closed

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Funded Activity Summary

Sphingosine kinase is a protein involved in cancer development and progression. We have identified that the cancer-inducing activity of sphingosine kinase is controlled by another protein called CIB1 which itself appears involved in causing cancer by deregulating sphingosine kinase. In this study we will examine and target the interaction between sphingosine kinase and CIB1 as a potential therapeutic intervention in cancer.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $805,034.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer cell biology | cell signalling | enzyme regulation | inhibitors | molecular basis of disease | protein localisation | protein structure

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