The role of adiponectin-mediated nitric oxide on portal hypertension and liver fibrosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1004595

Funding Status
Closed

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Funded Activity Summary

Liver cirrhosis is associated with high portal pressure that can result in severe bleeding and death. Adiponectin, a circulating protein, protects the liver from inflammation and scarring and may reduce portal pressure. We will characterise the mechanisms by which adiponectin induces NO and limits liver damage and determine if adiponectin treatment can reduce portal hypertension and bleeding in liver disease.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $526,380.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cirrhosis | fatty liver disease | hepatology | liver disease | liver fibrosis | nitric oxide | portal hypertension | stellate cells

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