Absence of CC chemokine receptor 6 dysregulates the humoral immune response.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1004592

Funding Status
Closed

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Funded Activity Summary

The individual steps leading to the activation and differentiation of B cells and the formation of mature functional germinal centres have been investigated in detail and are well understood. In contrast, the underlying molecular signals, which regulate the different events and prevent either autoimmunity or immunodeficiency are still not fully comprehended. This proposal will address these regulatory steps that prevent autoimmunity.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $524,820.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | autoimmune disease | cell migration | chemokine receptor | immune deficiency | lymphocytes | systemic lupus erythematosus (SLE)

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