Control of expression and activity of the ABCG1 cholesterol transporter in vascular cells

Funding Activity

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Funded Activity Summary

Atherosclerosis is the disease that narrows arteries and causes heart attacks, which kill many Australians. In the early stages of atherosclerosis, cholesterol builds up inside the cells in the walls of our blood vessels. In this project, we plan to study a molecule present in these cells that we think is important for exporting unwanted cholesterol. If we can find out how this molecule works, we may be able to design drugs to increase its capacity and hence prevent or reverse the process of atherosclerosis.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $389,546.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | cell biology | cholesterol metabolism | diabetes | heart disease | macrophage biology | transporters