Understanding the metabolic consequences of impaired AMPKa2 and nNOS� in skeletal muscle: implications for the Metabolic Syndrome

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1004212

Funding Status
Closed

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Funded Activity Summary

The inability of muscle to utilise sugar from the blood is a major problem that contributes to obesity and Type 2 diabetes. Since the number of people with these diseases will at least double by 2030, we need to find out what causes this problem. We will examine whether two muscle proteins that are impaired in obesity and Type 2 diabetes are also responsible for impaired sugar utilisation. We think that increasing these muscle proteins will fix the _sugar problem�, and remedy these diseases.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $575,527.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

carbohydrate metabolism | exercise intolerance | exercise physiology | insulin resistance | insulin sensitivity | mitochondrial function | obesity | skeletal muscle

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