POISE-2: A large, international, placebo-controlled, factorial trial to assess the impact of clonidine and aspirin in patients undergoing noncardiac surgery who are at risk of a perioperative cardiovascular event

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1004149

Funding Status
Closed

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Funded Activity Summary

At least 5 million patients annually worldwide suffer a heart attack or die after noncardiac surgery. Despite the magnitude of this problem, there are no good treatments to prevent these complications. Previous studies suggest that the drugs clonidine and aspirin may minimize the risk of heart attack after surgery. The POISE-2 trial will study 10,000 patients having noncardiac surgery to determine if clonidine and aspirin improve outcomes. This trial will influence the treatment of patients having surgery around the world.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $1,197,914.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cardiovascular pharmacology | cardiovascular risk | myocardial infarction | randomised controlled trial (RCT) | surgery

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