Investigating the role of the Notch4 receptor in blood vessel formation and remodelling in mammals

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1003209

Funding Status
Closed

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Funded Activity Summary

We aim to understand how blood vessels form. This process is crucial for foetal development, and for injury repair in adults. When there is too much or too little blood vessel formation, diseases such as arthritis, blindness and osteoporosis can result. Also many tumours grow and spread by growing new blood vessels. We will study a signal that occurs between cells (Notch signalling) that is important in controlling the amount of blood vessel formation, by analysing in detail one component (Notch4)

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $653,086.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Notch signalling pathway | angiogenesis | cancer progression | cardiovascular | embryonic development | mouse genetics | vascular development

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