Endocannabinoid-TRP interactions in midbrain analgesic pathways

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1003097

Funding Status
Closed

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Funded Activity Summary

Current pharmacotherapies for chronic pain are often ineffective. The active ingredient of the plant Cannabis sativa, THC, and a number of synthetic cannabinoids have efficacy in these pain states, however, they also produce a spectrum of adverse side-effects. This project will use cellular and behavioural techniques to examine how this cannabinoid system modulates intrinsic pain systems within the midbrain in order provide leads for novel analgesic pharmacotherapies with enhanced efficacy.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $586,903.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cannabinoid analgesics | chronic pain | drug discovery | neuropathic pain | neuropharmacology | pain | pain mechanisms | synaptic transmission

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