Investigating the Propagation of Protein Aggregation in Amyotrophic Lateral Sclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1003032

Funding Status
Closed

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Funded Activity Summary

Motor Neurone Disease is a rapidly progressive disease that attacks neurones responsible for controlling voluntary muscles, leading invariably to death. Currently there is no effective treatment. Recent work in humans suggests that degeneration begins focally and spreads through the three dimensional anatomy of the nervous system. This project will address the important question of how the toxicity is spread amongst adjacent neurones by characterising the propagation of protein aggregates.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $406,217.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

amyotrophic lateral sclerosis | astrocytes | frontotemporal dementia | motor neuron disease (MND) | protein aggregation

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