Production of interferon lambda by dendritic cell subsets and role in adjuvant effects of poly I:C

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1002903

Funding Status
Closed

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Funded Activity Summary

This proposal describes the identification of specific cells in mouse and humans that produce the anti-viral compound interferon-lambda. We propose to further characterise the mechanisms that induce interferon-lambda expression by these cell types and to decipher how this is controlled at the genetic level. We also aim to determine how the production of interferon lambda by these cell types can influence the immune response to viral infection.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $396,541.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adjuvant | dendritic cell | interferon (IFN) | vaccine design | viral immunity | viral infection

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