Roles of annexins in schistosome surface homeostasis and host-parasite interactions

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1002898

Funding Status
Closed

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Funded Activity Summary

With the increasing occurrence of the debilitating tropical disease schistosomiasis due to climate change, novel therapeutics are in demand. Current therapies rely on treatment with a single drug, and require repeated application. In this timely study, we will elucidate the role of surface-associated proteins, hypothesised to be the crucial stabilising factor in the body wall of the blood-feeding worm schistosome that protects the parasite. Targetting these proteins will lead to new therapeutics against schistosomiasis.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $612,885.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of Biological Macromolecules

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Schistosoma | drug development | host/pathogen interaction | infectious diseases | membrane protein | protein structure | schistosomiasis | vaccine candidate molecules

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