How Does A Host Cell Stimulatory Factor Stabilize The HIV-1 Reverse Transcription Complex?

Funding Activity

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Funded Activity Summary

We have identified a host cell activity which HIV uses to infect cells. The activity assists the uniques ability of HIV to convert its genome to a form which inserts itself into the host cell DNA. If we can identify the protein responsible for this activity we may be able to target it for drug development. Targetting host cell proteins rather than virus proteins for new drug may have advantages in preventing the acquisition of drug resistance.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $631,883.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

acquired immunodeficiency syndrome (AIDS) | antiviral agents | basic science | biochemistry | human immunodeficiency virus (HIV) | infectious diseases | molecular microbiology