Evaluating the link between the GPR91 receptor and renin in the pathogenesis of diabetic retinopathy

Funding Activity

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Funded Activity Summary

Diabetic retinopathy is the leading cause of blindness in people of working age. A hormonal system called renin-angiotensin is implicated in the development of diabetic retinopathy, and new evidence indicates that its blockade improves aspects of the disease. This project will examine if succinate/GPR91 mediates the over production of renin and represents an additional target for the treatment of diabetic retinopathy.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $486,824.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetes | diabetes mellitus | diabetic retinopathy | renin-angiotensin system (RAS) | treatment