Aquatic Animal Health Subprogram: development of a laboratory model for infectious challenge of Pacific oysters (Crassostrea gigas) with ostreid herpesvirus type-1

Funding Activity

Website
https://www.frdc.com.au/project/2012-052

Funding Status
Closed

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Funded Activity Summary

The need for further information to assist with the response to OsHV-1 is universally acknowledged by the aquaculture industry broadly, government agencies charged with biosecurity and aquatic animal health scientists in Australia and internationally.
Access to a standardised, reproducible and transferable laboratory infection model is critical to ongoing research efforts. Such a model provides a precise method of testing the effect of factors which are suspected to influence the outcome of an infectious challenge with OsHV-1 on Pacific oysters. The most promising factor for enabling continuation of Pacific oyster production despite the threat of OsHV-1 infection is the identification of genetic variation in susceptibility to POMS. The demand for efficient progress in selective breeding programmes requires a laboratory infection model which is suitable for screening large numbers of candidate families and provides results which can be reliably interpreted.


Objectives:
1. Production and long-term storage of large quantities of a standard OsHV-1 inoculum
2. Evaluation of methods to provide a standard, measured OsHV-1 infection challenge
3. Definition of the outcomes of infectious challenge including mortality, development of histopathological lesions and quantities of OsHV-1 present in tissues
4. Determination of the dose-response under standardised challenge conditions, including variation due to the age of the oysters
5. Determination of the repeatability, reproducibility and transferability of the standard infection challenge
6. Assessment of the susceptibility of flat oysters (spat and adult) to OsHV-1 infection.

Funded Activity Details

Start Date: 20-12-2012

End Date: 30-06-2014

Funding Scheme: Funding Scheme not available

Funding Amount: $134,990.00

Funder: Fisheries Research and Development Corporation

Research Topics

ANZSRC Field of Research (FoR)

There are no FoR codes available for this funding activity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Agriculture | Communications | Consumer | Disease | Modelling | Stakeholder

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