Linkage - International - Grant ID: LX0989187

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LX0989187

Funding Status
Closed

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Funded Activity Summary

Role of autophagy in degradation of endoplasmic reticulum (ER)-localised protein aggregates. This study will provide a new understanding of protein aggregate accumulation in the endoplasmic reticulum (ER), a phenomenon that occurs in aging cells and protein conformational diseases, and under stress conditions and during secretory protein overexpression. This information will inform strategies to prevent the onset of protein conformational diseases and help identify targets for pharmaceutical intervention. In addition, a powerful model system for studies of ER protein aggregation will be established, high-level training in biochemistry and morphometry will be provided, and an international collaboration of the highest calibre will be initiated.

Funded Activity Details

Start Date: 01-03-2009

End Date: 30-06-2010

Funding Scheme: Linkage - International

Funding Amount: $86,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Cell Metabolism | Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

Health related to ageing | Inherited diseases (incl. gene therapy) | Organs, diseases and abnormal conditions not elsewhere classified |

Other Keywords

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Cell Metabolism | Health related to ageing | Inherited diseases (incl. gene therapy) | Organs, diseases and abnormal conditions not elsewhere classified | Protein Targeting And Signal Transduction

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