Linkage - International - Grant ID: LX0881956

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LX0881956

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

A rational approach to a high-resolution structure of the multidrug transporter EmrE. Membrane proteins form only 0.3% of the available protein structures in the protein data bank (PDB), yet 30% of the proteins in the human genome and 50% of human drug targets are membrane proteins. Multidrug transporters are membrane proteins responsible for antibiotic resistance in humans. A high-resolution structure of a multidrug resistance protein, together with comprehensive biochemical characterization, would enable a detailed understanding of how these protein functions. Potentially it could also aid in the development of specific inhibitors that would prevent EmrE (and perhaps other similar proteins) from carry out its harmful mission.

Funded Activity Details

Start Date: 27-02-2008

End Date: 27-02-2009

Funding Scheme: Linkage - International

Funding Amount: $70,540.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Other Physical Sciences | Membrane Biology | Biophysics

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Chemical sciences |

Other Keywords

Biological sciences | Biophysics | Chemical sciences | Membrane Biology | Other Physical Sciences

Related Links