Linkage - International - Grant ID: LX0345926

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LX0345926

Funding Status
Closed

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Funded Activity Summary

Inhibitors of enzymes in the lysine biosynthetic pathway. Recent reports of increasing bacterial resistance to antibiotics highlight the need for continual development of new antibacterial agents. Inhibitors of the biosynthesis of the amino acid lysine - an essential component of bacterial proteins and cell wall - may provide a novel class of antibiotics. This project describes investigations of the mechanism of the first two enzymes in the lysine biosynthetic pathway and the design and synthesis of inhibitors of these enzymes.

Funded Activity Details

Start Date: 22-09-2003

End Date: 31-12-2006

Funding Scheme: Linkage - International

Funding Amount: $22,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medicinal and Biomolecular Chemistry | Biological And Medical Chemistry | Organic Chemical Synthesis

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Biological And Medical Chemistry | Infectious diseases | Medicinal and Biomolecular Chemistry | Organic Chemical Synthesis | Treatments (e.g. chemicals, antibiotics)

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