Linkage Projects - Grant ID: LP220200939

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP220200939

Funding Status
Active

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Funded Activity Summary

Designer Nanoparticles Enable mRNA Protein Factories. Intracellular delivery of mRNA facilitates target protein production, which could build protein factories that are essential in biomanufacturing industries. However, the instability of mRNA greatly lowers the protein production performance, limiting the commercial translation potential. This project aims to develop a new generation of nanoparticle delivery system to enhance mRNA stability against intracellular unstable cue, enzymatic digestion and thermal stress. This will be achieved by tailoring the nanochemistry at multi-scales. Expected outcomes include new knowledge in custom-design of functional nanomaterials for mRNA delivery, and new technology that will bring commercial benefits to the partner organisation and the biopharma sector.

Funded Activity Details

Start Date: 11-10-2023

End Date: 10-10-2026

Funding Scheme: Linkage Projects

Funding Amount: $402,115.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Materials engineering | Nanomaterials | Functional materials | Nanobiotechnology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Chemical Sciences | Functional materials | Materials engineering | Nanobiotechnology | Nanomaterials

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