Linkage Projects - Grant ID: LP200301120

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP200301120

Funding Status
Active

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Funded Activity Summary

Industrial biotechnology for the manufacture of alkaloid pharmaceuticals. Drugs that treat opioid dependence and overdose are increasingly needed but their manufacture is difficult, inefficient and expensive. This project aims to develop enzymatic N-demethylation as a simpler and more sustainable approach to the manufacture and modification of opioid antagonists, alkaloids and other drug targets. It will increase our understanding of enzymatic N-demethylation and address engineering and biotechnology challenges to improve yield and product isolation and concentration. Improvements in drug manufacturing processes will assist drug affected communities and industry will benefit from value adding, greater market share and flexibility, increased innovation and de-risked processes and new products.

Funded Activity Details

Start Date: 01-12-2021

End Date: 30-11-2024

Funding Scheme: Linkage Projects

Funding Amount: $522,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Industrial Biotechnology | Biocatalysis and Enzyme Technology | Interdisciplinary Engineering not elsewhere classified | Membrane and Separation Technologies

ANZSRC Socio-Economic Objective (SEO)

Industrial Crops not elsewhere classified | Expanding Knowledge in Engineering | Human Pharmaceutical Treatments (e.g. Antibiotics) |

Other Keywords

Biocatalysis and Enzyme Technology | Expanding Knowledge in Engineering | Human Pharmaceutical Treatments (e.g. Antibiotics) | Industrial Biotechnology | Industrial Crops not elsewhere classified | Interdisciplinary Engineering not elsewhere classified | Membrane and Separation Technologies

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