Linkage Projects - Grant ID: LP180100762

Funding Activity

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Funded Activity Summary

Molecular basis of attenuation in live Mycoplasma vaccines. This proposal aims to use an innovative approach to address an urgent issue raised by the end users of an Australian-owned poultry vaccine with an extensive global market. Recently multiple mutations have been detected in the vaccine re-isolated from vaccinated birds in the field around the world. We will apply a combination of a novel technique for targeted mutagenesis, genome sequencing, and animal experimentations, to address the significance of these mutations. Results will improve our understanding of the basis of attenuation of the vaccine, its mechanism of action, and provide commercial confidence in the safety of the vaccine, which is needed to support Australian Universities and Businesses, and the global poultry industry.

Funded Activity Details

Start Date: 06-01-2020

End Date: 29-08-2024

Funding Scheme: Linkage Projects

Funding Amount: $413,981.00

Funder: Australian Research Council