Linkage Projects - Grant ID: LP160101757

Funding Activity

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Funded Activity Summary

Investigating the structure of a T cell immune checkpoint molecule. This project aims to investigate the basic structure and function of a key co-receptor expressed on T cells, known as lymphocyte activation gene-3. T cells play a role in the immune system but must be managed to prevent autoimmunity. Insight into the function of the lymphocyte activation gene-3 function can be used to tailor immunotherapeutics to treat a variety of diseases, including cancer. Functionality of the T cell receptor is determined by utilising structural biology and cellular immunology techniques. The impact of this project effects the development of innovative T cell immunomodulatory agents, improving the health and quality of life of the Australian population.

Funded Activity Details

Start Date: 29-08-2017

End Date: 31-12-2020

Funding Scheme: Linkage Projects

Funding Amount: $360,000.00

Funder: Australian Research Council