Linkage Projects - Grant ID: LP160100325

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP160100325

Funding Status
Closed

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Funded Activity Summary

Interrogating protein hydration by terahertz time-domain spectroscopy. Interrogating protein hydration by terahertz time-domain spectroscopy. This project aims to develop advanced terahertz time-domain spectroscopy (THz-TDS) techniques to understand how a protein’s interaction with excipients in solution can alter the hydration layers around them and how this affects properties such as viscosity and stability. THz-TDS can detect overlapping extended hydration layers around proteins, revealing new knowledge in protein-protein interactions and protein behaviour in an aqueous environment. The intended outcome is to use THz-TDS to better understand how proteins such as monoclonal antibodies interact in high concentration solutions, and in doing so make better medicines.

Funded Activity Details

Start Date: 09-11-2016

End Date: 31-12-2020

Funding Scheme: Linkage Projects

Funding Amount: $270,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Electrical and Electronic Engineering | Photonics and Electro-Optical Engineering (excl. Communications) | Biomedical Instrumentation | Interdisciplinary Engineering not elsewhere classified |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Medical and Health Sciences | Expanding Knowledge in Technology

Other Keywords

Biomedical Instrumentation | Electrical and Electronic Engineering | Expanding Knowledge in Technology | Expanding Knowledge in the Medical and Health Sciences | Expanding Knowledge in the Physical Sciences | Interdisciplinary Engineering not elsewhere classified | Photonics and Electro-Optical Engineering (excl. Communications)

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