Linkage Projects - Grant ID: LP160100182

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP160100182

Funding Status
Closed

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Funded Activity Summary

Industrial biotechnology for improved manufacture of medicinal alkaloids. Industrial biotechnology for improved manufacture of medicinal alkaloids. This project aims to develop a new semi-synthetic route for the manufacture of Codeine from Thebaine. Codeine is manufactured by the chemical conversion of poppy-derived Morphine, which is low yielding and environmentally unfriendly. This project will investigate and optimise two key enzymes in the biosynthetic pathway to Codeine and develop an innovative bioreactor to achieve high yield. It will research industrial biotransformations, providing a greener and cheaper process for increased global access to Codeine. Australian opiate manufacturing is expected to benefit from value adding and increased flexibility introduced by a biotechnology approach.

Funded Activity Details

Start Date: 23-11-2016

End Date: 22-11-2019

Funding Scheme: Linkage Projects

Funding Amount: $305,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Industrial Biotechnology | Biocatalysis and Enzyme Technology | Membrane and Separation Technologies

ANZSRC Socio-Economic Objective (SEO)

Industrial Crops not elsewhere classified | Human Pharmaceutical Treatments (e.g. Antibiotics) |

Other Keywords

Biocatalysis and Enzyme Technology | Human Pharmaceutical Treatments (e.g. Antibiotics) | Industrial Biotechnology | Industrial Crops not elsewhere classified | Membrane and Separation Technologies

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