Linkage Projects - Grant ID: LP150101226

Funding Activity

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Funded Activity Summary

An Open Source Approach to Understanding an Important Parasite Ion Pump. This project plans to synthesise new compounds that bind the protein ATP4, an essential ion pump in the malaria parasite. It plans to generate a three-dimensional map to understand how these compounds stop ATP4 from working. Several promising new medicines for malaria target ATP4, yet we do not understand properly how they do so. The project’s intended aims will be achieved using new methods in synthetic chemistry and membrane biology, and by leveraging global scientific inputs through online research methods allowing anyone to participate.

Funded Activity Details

Start Date: 03-12-2015

End Date: 31-12-2019

Funding Scheme: Linkage Projects

Funding Amount: $410,000.00

Funder: Australian Research Council