Linkage Projects - Grant ID: LP150101014

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP150101014

Funding Status
Closed

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Funded Activity Summary

A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of interest to capture the miRNA. Application of a magnetic field allows the levels of miRNA to be detected electrochemically. The expected outcome is a commercialisable biosensor for miRNA both as a diagnostic early detection device and a prognostic device for a range of miRNA biomarkers.

Funded Activity Details

Start Date: 01-11-2016

End Date: 31-05-2020

Funding Scheme: Linkage Projects

Funding Amount: $410,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Analytical Chemistry | Sensor Technology (Chemical aspects) | Electroanalytical Chemistry

ANZSRC Socio-Economic Objective (SEO)

Diagnostic Methods | Scientific Instruments |

Other Keywords

Analytical Chemistry | Diagnostic Methods | Electroanalytical Chemistry | Scientific Instruments | Sensor Technology (Chemical aspects)

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