Linkage Projects - Grant ID: LP150100737

Funding Activity

Website
https://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP150100737

Funding Status
Closed

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Funded Activity Summary

A new biomechanical model for understanding aging of stored Red Blood Cells. This project plans to develop a novel modelling framework to accurately represent the biomechanical properties of red blood cells (RBCs) over time under stored conditions. Stored RBCs suffer ageing-related deformability changes which impede RBC functions. The framework aims to integrate models for RBC membrane, inside haemoglobin and outside storage solution, and accounts for ageing effects by embedding time-dependent correlations. It should provide new insights and understanding of the mechanisms of deformability changes of RBCs during stored lifespan. Therefore, it should significantly improve blood storage industry practices in terms of improving RBC storage protocols with preventative ageing strategies.

Funded Activity Details

Start Date: 22-10-2015

End Date: 31-12-2019

Funding Scheme: Linkage Projects

Funding Amount: $350,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomechanical Engineering | Mechanical Engineering | Numerical Modelling and Mechanical Characterisation

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in Engineering | Health and Support Services not elsewhere classified |

Other Keywords

Biomechanical Engineering | Expanding Knowledge in Engineering | Health and Support Services not elsewhere classified | Mechanical Engineering | Numerical Modelling and Mechanical Characterisation

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