Linkage Projects - Grant ID: LP140100920

Funding Activity

Website
https://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP140100920

Funding Status
Closed

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Funded Activity Summary

Exploring the immunomodulatory potential of Natural Killer T cells. Natural Killer T cells (NKT cells) are an innate-like population of T cells that recognise a range of lipid based antigens when bound to the antigen-presenting molecule, CD1d. Once activated, NKT cells rapidly secrete a variety of cytokines. This project, in partnership with Vaxine Pty Ltd, aims to gain a basic understanding of NKT recognition of lipids and NKT cell activation by lipids. The project aims to use a combination of cellular immunology and structural biology to gain insight into NKT cell agonism.

Funded Activity Details

Start Date: 31-12-2014

End Date: 30-06-2018

Funding Scheme: Linkage Projects

Funding Amount: $590,922.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies) | Biochemistry and Cell Biology | Receptors and Membrane Biology | Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

Human Biological Preventatives (e.g. Vaccines) | Expanding Knowledge in the Biological Sciences |

Other Keywords

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies) | Biochemistry and Cell Biology | Expanding Knowledge in the Biological Sciences | Human Biological Preventatives (e.g. Vaccines) | Receptors and Membrane Biology | Structural Biology (incl. Macromolecular Modelling)

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