Linkage Projects - Grant ID: LP100200156

Funded Activity Summary

Engineering pressurized liquid droplets to generate high-efficiency aerosols for targeted respiratory delivery. Many macroscopic aspects of pressurised Metered Dose Inhaler (pMDI) for respiratory diseases are recognised, but are yet to be understood at the basic level and accordingly exploited. In particular, the droplet charge mechanism in non-aqueous pMDIs remains elusive. Currently, although a wide range of drugs are commercially available as pMDIs, the efficiency of these systems is poor, with most devices delivering less than 20 per cent to the lung. An insight into these systems is crucial to successfully enhance the performance of aerosol formulations in industry, ultimately translating into superior patient therapy. This project will create a theoretical model for pMDI formulation that can be applied to the development of a new generation of inhalation medicines.

Funded Activity Details

Start Date: 05-05-2011

End Date: 05-05-2016

Funding Scheme: Linkage Projects

Funding Amount: $290,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences | Pharmaceutical Sciences | Materials Engineering not elsewhere classified | Chemical Characterisation of Materials

ANZSRC Socio-Economic Objective (SEO)

Respiratory System and Diseases (incl. Asthma) | Human Pharmaceutical Products not elsewhere classified | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Chemical Characterisation of Materials | Expanding Knowledge in the Medical and Health Sciences | Human Pharmaceutical Products not elsewhere classified | Materials Engineering not elsewhere classified | Pharmaceutical Sciences | Pharmacology and Pharmaceutical Sciences | Respiratory System and Diseases (incl. Asthma)

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