Linkage Projects - Grant ID: LP100200021

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP100200021

Funding Status
Closed

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Funded Activity Summary

Life at the nanometre scale: imaging immunological synapses with a novel super-resolution fluorescence microscope. This project aims to image individual proteins in activated white blood cells in order to understand how lymphocytes participate in an immune response. The problem is that current imaging modalities either lack resolution or are unsuitable for live cell and three-dimensional (3D) imaging. With the project’s industry partner, Carl Zeiss MicroImaging, the project will build and apply a novel microscope that is capable of visualising single proteins in 3D and live cells. This technology will provide insights into signalling and lymphocyte function on a true molecular scale.

Funded Activity Details

Start Date: 18-03-2011

End Date: 31-12-2014

Funding Scheme: Linkage Projects

Funding Amount: $425,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Receptors and Membrane Biology | Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Health not elsewhere classified |

Other Keywords

Biochemistry and Cell Biology | Expanding Knowledge in the Biological Sciences | Health not elsewhere classified | Receptors and Membrane Biology | Signal Transduction

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