Linkage Projects - Grant ID: LP0669658

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0669658

Funding Status
Closed

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Funded Activity Summary

Structure-based inhibitor design of VAP-1/SSAO for the treatment of respiratory dirsorders and other major inflammatory diseases. Inflammatory diseases, such as asthma, rheumatoid arthritis and multiple sclerosis, are widespread and often poorly treated in Australia and elsewhere. Inhibitors of the recently studied VAP-1/SSAO protein are predicted to effectively treat the inflammation symptoms of one or more of these diseases. A structure-based approach to discover these new medicines should provide a means to identify patentable compounds, with high potency, efficacy and safety. If this approach is successful, an Australian pharmaceutical company will be one of the first to the market with this new medicine to treat these chronic diseases.

Funded Activity Details

Start Date: 28-02-2007

End Date: 26-08-2010

Funding Scheme: Linkage Projects

Funding Amount: $290,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Medical Biochemistry and Metabolomics | Medical Biochemistry: Proteins And Peptides | Biological And Medical Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Immune system and allergy | Treatments (e.g. chemicals, antibiotics)

Other Keywords

Biological And Medical Chemistry | Enzymes | Immune system and allergy | Medical Biochemistry and Metabolomics | Medical Biochemistry: Proteins And Peptides | Treatments (e.g. chemicals, antibiotics)

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