Linkage Projects - Grant ID: LP0668324

Funding Activity

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Funded Activity Summary

Systematic evaluation of whether in vitro methods can predict in vivo opioid analgesic efficacy, safety and tolerability. It is estimated that chronic pain affects one in five individuals in the general community in Australia and worldwide, with prevalence rates correlated directly with advancing age. Chronic pain not only adversely affects the quality of life of individuals but it also places a large economic burden on our healthcare system. Development and validation of an in vitro method to successfully identify novel morphine-like strong analgesics with a reduced propensity for producing respiratory depression or constipation, has the potential to not only improve pain management for individuals and to reduce the economic burden of chronic pain on the Australian healthcare system, but it is also likely to produce direct economic benefits to our nation.

Funded Activity Details

Start Date: 20-03-2006

End Date: 31-03-2010

Funding Scheme: Linkage Projects

Funding Amount: $372,000.00

Funder: Australian Research Council