Linkage Projects - Grant ID: LP0562190

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0562190

Funding Status
Closed

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Funded Activity Summary

Devil Facial Tumour Disease: Cytogenetic Clues to Transmission and Development. Devil Facial Tumour Disease is a fatal cancer that is decimating Tasmanian devils. Preliminary work suggests that tumours from different animals have identical sets of highly abnormal chromosomes, including a giant marker chromosome. We will use DNA probes to 'paint' abnormal tumour chromosomes to discover markers for diagnosis, and identify genes contributing to tumour development and immune suppression. Most importantly, we will test our hypothesis that tumours all arose from a single ancestral cancer cell that is transmitted between animals. A cellular transmission has frightening implications for spread of disease, but will allow us to develop appropriate therapeutic strategies to save a unique Australian marsupial from extinction.

Funded Activity Details

Start Date: 21-12-2005

End Date: 31-07-2009

Funding Scheme: Linkage Projects

Funding Amount: $117,444.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Veterinary Sciences | Pathology | Oncology And Carcinogenesis | Population And Ecological Genetics

ANZSRC Socio-Economic Objective (SEO)

Living resources (flora and fauna) | Diagnostics | Cancer and related disorders |

Other Keywords

Cancer and related disorders | Diagnostics | Living resources (flora and fauna) | Oncology And Carcinogenesis | Pathology | Population And Ecological Genetics | Veterinary Sciences

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