Linkage Projects - Grant ID: LP0561097

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0561097

Funding Status
Closed

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Funded Activity Summary

Proteomics Analysis of Interactions Between Chaperonin 10 and Cell Surface Proteins. Specific interactions at the cell surface may induce downstream biological responses. In the case of chaperonin 10, Cpn10, interaction at the cell surface results in immunomodulation of the inflammatory response. Cell surface proteins that interact with Cpn10 have not been identified. This project will use chemical crosslinking and proteomic techniques to identify cell surface proteins that interact with Cpn10 and structural features of Cpn10 involved in these interactions. These findings will providde leads for the development of immunomodulatory therapeutics based on Cpn10 interactions. Analytical technologies will be developed that are applicable to other interacting protein systems.

Funded Activity Details

Start Date: 14-02-2005

End Date: 13-02-2008

Funding Scheme: Linkage Projects

Funding Amount: $300,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Analytical Biochemistry | Biotechnology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

Immune system and allergy | Health related to ageing | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Analytical Biochemistry | Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Biotechnology Not Elsewhere Classified | Health related to ageing | Immune system and allergy | Treatments (e.g. chemicals, antibiotics)

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