Linkage Projects - Grant ID: LP0561064

Funding Activity

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Funded Activity Summary

Novel Technologies for the Purification of Recombinant Proteins. Availability of enabling technologies for the large-scale purification of recombinant proteins is an essential requirement of the biotechnology industry. This project aims to integrate two concepts in molecular biorecognition. New modalities of immobilised metal ion affinity chromatography will be linked with the selection of new types of peptide affinity handles that can be inserted by genetic engineering methods into proteins produced by biotechnological procedures. The approach followed then allows these handles to be removed following isolation of the target protein. This project could thus lead to a considerable advance in the manufacture of recombinant proteins intended for human therapy.

Funded Activity Details

Start Date: 30-03-2005

End Date: 31-12-2008

Funding Scheme: Linkage Projects

Funding Amount: $1,160,021.00

Funder: Australian Research Council