Linkage Projects - Grant ID: LP0560526

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0560526

Funding Status
Closed

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Funded Activity Summary

Genetic manipulation of Clostridium sporogenes. The overall objective of this project is to develop genetic methods for the manipulation of the anaerobic bacterium Clostridium sporogenes. Specifically, the project aims to manipulate this microorganism so that genes encoding enzymes that convert prodrugs to anticancer drugs can be introduced and stably maintained on its chromosome. The significance of the project is that the resultant bacteria, and others constructed using these methods, will then be able to be tested for their ability to act as specific drug delivery systems for use in the treatment of solid tumours.

Funded Activity Details

Start Date: 01-01-2005

End Date: 31-12-2008

Funding Scheme: Linkage Projects

Funding Amount: $160,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbial Genetics | Oncology And Carcinogenesis | Microbiology | Biotechnology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

Treatments (e.g. chemicals, antibiotics) | Cancer and related disorders | Biological sciences |

Other Keywords

Biological sciences | Biotechnology Not Elsewhere Classified | Cancer and related disorders | Microbial Genetics | Microbiology | Oncology And Carcinogenesis | Treatments (e.g. chemicals, antibiotics)

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