Linkage Projects - Grant ID: LP0455701

Funding Activity

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Funded Activity Summary

Oral Insulin Delivery facilitated by Enteric Coating using Dense Gas Technologies. Insulin dependant diabetes is a rapidly growing disease. The current method for insulin delivery to the patient is by injection, which is inconvenient. Oral delivery of insulin is a more acceptable method. It is proposed to develop a dense gas technique to coat insulin with a pH sensitive polymer to protect it from the acidic environment of the stomach. Insulin can then be released at the high pH of the intestine when the polymer is dissolved. Particle size control is feasible by dense gas processes by manipulating operating parameters. Advantages include low residual solvent and manufacture at ambient temperatures.

Funded Activity Details

Start Date: 07-02-2005

End Date: 07-08-2008

Funding Scheme: Linkage Projects

Funding Amount: $254,000.00

Funder: Australian Research Council