Linkage Projects - Grant ID: LP0455407

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0455407

Funding Status
Closed

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Funded Activity Summary

Novel Glycoproteomic based diagnostic technology for identifying cartilage tissue turnover and repair. Osteoarthritis is a long-term debilitating disease, which results in the loss of cartilage in the joints, leading to pain and disability. This is a major problem and cost in ageing societies, yet the mechanisms of joint deterioration are still poorly understood. This project will investigate proteoglycans and proteoglycan fragments produced by cells of the joint, detailing the structure of their sugar components, and map which regions are interacting with antibodies. Understanding these proteoglycan fragments will help us to determine their role in disease progression, and application of this knowledge will assist in the development of an early diagnostic for osteoarthritis.

Funded Activity Details

Start Date: 01-07-2004

End Date: 31-12-2008

Funding Scheme: Linkage Projects

Funding Amount: $389,997.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomedical Engineering Not Elsewhere Classified | Orthopaedics | Biochemistry and Cell Biology | Analytical Biochemistry |

ANZSRC Socio-Economic Objective (SEO)

Skeletal system and disorders (incl. arthritis) | Diagnostics | Health status (e.g. indicators of “well-being”)

Other Keywords

Analytical Biochemistry | Biochemistry and Cell Biology | Biomedical Engineering Not Elsewhere Classified | Diagnostics | Health status (e.g. indicators of “well-being”) | Orthopaedics | Skeletal system and disorders (incl. arthritis)

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