Linkage Projects - Grant ID: LP0455373

Funding Activity

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Funded Activity Summary

Synthesis of new heterocyclic analogues of isoflavones. Intake of high dietary isoflavonoid phytoestrogens has been linked to low prevalence of hormone-dependent cancers such as breast and prostate cancer, and heart disease. The isoflavones resemble endogenous estradiol in structure, and have been shown to display weak estrogenic activity. Novogen Limited is pioneering the development of novel drug candidates based on isoflavones. This collaborative research project deals with the development of synthetic methodologies for the preparation of new analogues of isoflavone metabolites as potential drug candidates. The target compounds will be evaluated for possible therapeutic use by the industry partner.

Funded Activity Details

Start Date: 01-01-2004

End Date: 31-12-2008

Funding Scheme: Linkage Projects

Funding Amount: $70,668.00

Funder: Australian Research Council