Linkage Projects - Grant ID: LP0455306

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0455306

Funding Status
Closed

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Funded Activity Summary

Identification and characterisation of Mycoplasma hyopneumoniae surface-molecules that interact with the host epithelium. Mycoplasma hyponeumoniae causes porcine enzootic pneumonia, a disease that significantly impacts swine production. Current vaccines are unable to prevent colonisation of the respiratory tract and are costly to produce and administer. The expression of microbial adhesins that mediate adherence to the extracellular matrix is considered the initial step in host colonisation for many bacterial pathogens. We propose to identify M. hyopneumoniae cell surface moleculaes that interact with components of the extracellular matrix. Targetting these cell surface molecules will lead to therapeutics that prevent disease and block colonisation, eventually eradicating the host pathogen from pig production facilities.

Funded Activity Details

Start Date: 02-09-2004

End Date: 27-09-2008

Funding Scheme: Linkage Projects

Funding Amount: $468,557.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbiology (Excl. Virology) | Animal Protection (Pests And Pathogens) | Bacteriology | Microbiology

ANZSRC Socio-Economic Objective (SEO)

Pigs |

Other Keywords

Animal Protection (Pests And Pathogens) | Bacteriology | Microbiology | Microbiology (Excl. Virology) | Pigs

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