Linkage Projects - Grant ID: LP0454285

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0454285

Funding Status
Closed

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Funded Activity Summary

Rational structure-based drug design of protein tyrosine kinase inhibitors. Protein tyrosine kinases (PTK) are a large, pivotal family of signalling molecules implicated in diseases such as cancer and immune-related disorders, that cause significant morbidity and mortality within the population. This research proposal aims to develop PTK-specific small molecule inhibitors to combat such diseases. Cytopia's drug discovery capability, coupled with the X-ray crystallographic expertise within Monash University, will permit a rational, structure-based drug discovery platform to be established. The ultimate goal of this innovative and mutlidisciplinary approach, namely a portfolio of phase I therapeutics, will be of substantial benefit in the medical health area.

Funded Activity Details

Start Date: 29-06-2004

End Date: 31-12-2008

Funding Scheme: Linkage Projects

Funding Amount: $1,200,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Biotechnology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

Immune system and allergy | Cancer and related disorders |

Other Keywords

Biochemistry and Cell Biology | Biotechnology Not Elsewhere Classified | Cancer and related disorders | Immune system and allergy | Protein Targeting And Signal Transduction

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