Linkage Projects - Grant ID: LP0454035

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0454035

Funding Status
Closed

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Funded Activity Summary

Chemoenzymatic Routes to Novel Dendritic Architectures Suitable for Pharmaceutical Applications. Dendritic molecules incorporating multiple copies of a particular functional group on their periphery allow for attachment of drug-like molecules at each of these sites. The resulting conjugates often have vastly superior therapeutic properties relative to the original single drug molecule. This phenomenon is now revolutionizing drug design. Developments in this area are limited by the range of dendritic molecules currently available. Thus, lack of variation in the three-dimensional architecture and the functionality available at the periphery of such constructs is a serious deficiency. This proposal seeks to redress this through the application of novel chemoenzymatic methods developed by the applicant.

Funded Activity Details

Start Date: 19-03-2004

End Date: 18-03-2007

Funding Scheme: Linkage Projects

Funding Amount: $70,668.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organic Chemistry | Biological And Medical Chemistry | Organic Chemical Synthesis |

ANZSRC Socio-Economic Objective (SEO)

Respiratory system and diseases (incl. asthma) | Prevention—biologicals (e.g. vaccines) | Treatments (e.g. chemicals, antibiotics)

Other Keywords

Biological And Medical Chemistry | Organic Chemical Synthesis | Organic Chemistry | Prevention—biologicals (e.g. vaccines) | Respiratory system and diseases (incl. asthma) | Treatments (e.g. chemicals, antibiotics)

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