Linkage Projects - Grant ID: LP0347486

Funding Activity

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Funded Activity Summary

Synthetic compounds to specifically activate or inhibit ryanodine receptor calcium ion channels. The aim of the project is develop synthetic compounds that specifically and reversibly activate or inhibit ryanodine receptor calcium release channels, and will thus increase or reduce the force developed by skeletal muscle and the heart. The compounds will be useful in biomedical and veterinary sciences and in the livestock industry. Some of the compounds that are not effective on mammalian ryandine receptor isoforms might interact with insect channels and provide a template for a new class of insecticides. The compounds will be based on naturally occurring peptides which specifically and reversibly modulate mammalian calcium channels.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2005

Funding Scheme: Linkage Projects

Funding Amount: $204,000.00

Funder: Australian Research Council