Linkage Projects - Grant ID: LP0347272

Funding Activity

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Funded Activity Summary

Molecular Interactions of Chemical Agents with Ion-Channel Proteins. With a minimal number of functional units (proteins) viruses are able to replicate. All of these proteins are possible antiviral targets. In this project we wil1 focus on a short protein called Vpu found in membranes of the HIV-1 virus and aim to analyse the interaction of potential pore blocking compounds. It is essential to know exactly where they sit and how the overall structure of Vpu is affected. For this enterprise we will use nuclear magnetic resonance (NMR) spectroscopy. This information will serve as a springboard for future investigations of virus membrane proteins.

Funded Activity Details

Start Date: 29-04-2003

End Date: 31-12-2005

Funding Scheme: Linkage Projects

Funding Amount: $210,000.00

Funder: Australian Research Council