Linkage Projects - Grant ID: LP0211586

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0211586

Funding Status
Closed

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Funded Activity Summary

Molecular and antibody analysis of cytomegalovirus (CMV) infection of fetal and placental cells. CMV is a beta herpesvirus with many unknown molecular mechanisms associated with cellular infection. The virus infects placental cells in vivo, although pathogenesis of viral damage to these cells has been extremely difficult to study in vitro. We have commenced a study to i) demonstrate the molecular accompaniments of infection of placental cells in vitro, ii) determine the genotypic characteristics of congenital CMV infections, in collaboration with Abbott Diagnostics, and iii) produce an in vivo model of CMV infection to demonstrate the pathogenesis of cellular injury. The combination of molecular expertise at UNSW with monoclonal antibody expertise from Abbott Diagnostics mean this project is unique worldwide.

Funded Activity Details

Start Date: 17-12-2002

End Date: 16-12-2005

Funding Scheme: Linkage Projects

Funding Amount: $137,679.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Diagnostic Applications | Paediatrics | Microbiology | Virology

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Prevention—biologicals (e.g. vaccines) | Child health |

Other Keywords

Child health | Diagnostic Applications | Infectious diseases | Microbiology | Paediatrics | Prevention—biologicals (e.g. vaccines) | Virology

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